Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711206 | 0.98 | TSHR (0.57) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL6913054 | 0.96 | TSHR (0.55) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL6915523 | 0.96 | TSHR (0.55) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27892853 | 0.96 | TSHR (0.55) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL6914622 | 0.96 | TSHR (0.55) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL6918780 | 0.96 | TSHR (0.55) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL6917498 | 0.96 | TSHR (0.55) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL6914906 | 0.96 | TSHR (0.55) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL6915527 | 0.96 | TSHR (0.55) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL6916893 | 0.96 | TSHR (0.55) | TSHRALDH1A1HSD17B10TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574076-B | Preparation method of difluoromethyl sulfone compound | 中国科学院上海有机化学研究所 | 2022-08-09 | — | — | CN | disclosed |
| CN-112142656-B | Sulfonyl pyridine amide derivatives and preparation method thereof | 杭州职业技术学院 | 2022-03-18 | — | — | CN | disclosed |
| CN-112142656-A | Sulfonyl pyridine amide derivatives and preparation method thereof | 杭州职业技术学院 | 2020-12-29 | — | — | CN | disclosed |