Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31717021 | 0.81 | SMN1; SMN2 (0.43) | MAOBSMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL21752440 | 0.81 | SMN1; SMN2 (0.58) | MAOBSMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL31716649 | 0.79 | SMN1; SMN2 (0.41) | MAOBSMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL21752735 | 0.79 | TDP1 (0.43) | MAOBSMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL5055395 | 0.75 | POLB (0.40) | MAOBSMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL18578663 | 0.75 | PIK3CG (0.54) | MAOBSMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL29707245 | 0.69 | FFAR1 (0.38) | SMN1; SMN2RAB9AMAPTNPC1L3MBTL1 | |
| SCHEMBL18717549 | 0.68 | POLB (0.46) | MAOBSMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL13960990 | 0.68 | KDR (0.37) | MAOBSMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL28560844 | 0.67 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9AMAPTNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574211-B | Heterocyclic kinase inhibitors | 山东轩竹医药科技有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-112574211-A | Heterocyclic kinase inhibitors | 山东轩竹医药科技有限公司 | 2021-03-30 | — | — | CN | disclosed |