SCHEMBL2856151

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6032268	0.89	MAPT (0.49)	ADRB2ADRB1ADRB3SMN1; SMN2NPC1
	SCHEMBL2858288	0.89	FLT3 (0.43)	ADRB2ADRB1ADRB3VNN1SMN1; SMN2
	SCHEMBL2866520	0.89	KDM4E (0.39)	ADRB2ADRB1ADRB3SMN1; SMN2NPC1
	SCHEMBL2861148	0.88	KDM4E (0.40)	ADRB2ADRB1ADRB3SMN1; SMN2NPC1
	SCHEMBL2871401	0.87	MAPT (0.42)	ADRB2ADRB1ADRB3SMN1; SMN2NPC1
	SCHEMBL2857454	0.83	KDM4E (0.43)	ADRB2ADRB1ADRB3VNN1SMN1; SMN2
	SCHEMBL2861694	0.83	KDM4E (0.45)	SMN1; SMN2NPC1POLBMAPTRAB9A
	SCHEMBL2857059	0.82	KDM4E (0.44)	SMN1; SMN2NPC1POLBMAPTRAB9A
	SCHEMBL2866300	0.82	KDM4E (0.38)	ADRB2ADRB1ADRB3SMN1; SMN2NPC1
	SCHEMBL2866357	0.81	KDM4E (0.36)	ADRB2ADRB1ADRB3SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.