Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.88 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | SNCA | P37840 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | DPP4 | P27487 | 3/20 | 0.63 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.61 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.61 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.61 |
| ▸ | CTSL | P07711 | 1/20 | 0.61 |
| ▸ | CTSB | P07858 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15155042 | 0.88 | ABCG2 (0.88) | ABCG2LMNAMAPTSMN1; SMN2SNCA | |
| SCHEMBL15155043 | 0.88 | ABCG2 (0.88) | ABCG2LMNAMAPTSMN1; SMN2SNCA | |
| SCHEMBL7101429 | 0.87 | ABCG2 (0.85) | ABCG2MEN1KMT2ALMNAGAA | |
| SCHEMBL7099872 | 0.84 | ABCG2 (0.81) | ABCG2MEN1KMT2ALMNAGAA | |
| SCHEMBL30307319 | 0.84 | ABCG2 (0.89) | ABCG2LMNAMAPTSMN1; SMN2CAPN1 | |
| SCHEMBL31441472 | 0.84 | DPP4 (0.83) | ABCG2SNCADPP4CXCL12PTPN1 | |
| SCHEMBL1352837 | 0.83 | ABCG2 (0.64) | ABCG2MEN1KMT2ALMNAGAA | |
| SCHEMBL1352832 | 0.83 | ABCG2 (0.64) | ABCG2MEN1KMT2ALMNAGAA | |
| SCHEMBL7184368 | 0.81 | DPP4 (0.74) | ABCG2SNCADPP4CAPN1CTSL | |
| SCHEMBL9111983 | 0.81 | TNFRSF1A (0.72) | ABCG2LMNAMAPTSMN1; SMN2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112826812-B | Pharmaceutical composition for treating colon cancer and application thereof | 青岛大学 | 2023-08-25 | — | — | CN | claimed |
| CN-112694392-B | TRPV3 inhibitor and preparation method thereof | 青岛大学 | 2022-11-22 | — | — | CN | claimed |
| CN-112826812-A | Pharmaceutical composition for treating colon cancer and application thereof | 青岛大学 | 2021-05-25 | — | — | CN | claimed |
| CN-112826812-B | Pharmaceutical composition for treating colon cancer and application thereof | 青岛大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-112694392-B | TRPV3 inhibitor and preparation method thereof | 青岛大学 | 2022-11-22 | — | — | CN | disclosed |
| CN-112826812-A | Pharmaceutical composition for treating colon cancer and application thereof | 青岛大学 | 2021-05-25 | — | — | CN | disclosed |
| CN-112694392-A | TRPV3 inhibitor and preparation method thereof | 青岛大学 | 2021-04-23 | — | — | CN | disclosed |