Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21626592 | 0.90 | MEN1 (0.39) | PTPN1ACEMAPK1YAP1KMT2A | |
| SCHEMBL21626593 | 0.90 | MEN1 (0.39) | PTPN1ACEMAPK1YAP1KMT2A | |
| SCHEMBL28562103 | 0.90 | PTPN1 (0.42) | PTPN1ACEMAPK1YAP1ATM | |
| SCHEMBL21626600 | 0.85 | MEN1 (0.35) | PTPN1YAP1KMT2AMEN1 | |
| SCHEMBL21626599 | 0.85 | MEN1 (0.35) | PTPN1YAP1KMT2AMEN1 | |
| SCHEMBL28555844 | 0.84 | PTPN1 (0.36) | PTPN1YAP1SCN9ACYP3A4 | |
| SCHEMBL20437153 | 0.82 | MEN1 (0.42) | PTPN1ACEKMT2AMEN1ITGA4 | |
| SCHEMBL23813319 | 0.81 | KMT2A (0.40) | KMT2AMEN1SCN9A | |
| SCHEMBL23799253 | 0.80 | MEN1 (0.41) | PTPN1ACEKMT2AMEN1ITGA4 | |
| SCHEMBL23799254 | 0.80 | MEN1 (0.41) | PTPN1ACEKMT2AMEN1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112752757-A | Tyrosine amide derivatives as RHO-kinase inhibitors | 奇斯药制品公司 | 2021-05-04 | — | — | CN | disclosed |