Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28573427 | 0.82 | SMYD2 (0.34) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL29846198 | 0.79 | ACACB (0.34) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL30943561 | 0.76 | SMYD2 (0.32) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL21784327 | 0.74 | SMYD2 (0.36) | SMYD2CYP3A4HTTSMN1; SMN2PSMB5 | |
| SCHEMBL29469759 | 0.74 | SMYD2 (0.34) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL25653647 | 0.74 | SMYD2 (0.34) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL4120527 | 0.72 | SMYD2 (0.35) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL17768505 | 0.72 | SMYD2 (0.35) | SMYD2CYP3A4HTTSMN1; SMN2PSMB5 | |
| SCHEMBL20253982 | 0.70 | SMYD2 (0.41) | SMYD2CYP3A4HTTSMN1; SMN2PSMB5 | |
| SCHEMBL1566807 | 0.70 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112789085-A | Compounds useful in HIV therapy | 葛兰素史克知识产权第二有限公司 | 2021-05-11 | — | — | CN | disclosed |