Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.69 |
| ▸ | CD63 | P08962 | 2/20 | 0.68 |
| ▸ | JAK2 | O60674 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15551918 | 0.88 | SYK (0.69) | SYKCD63JAK2 | |
| SCHEMBL16851493 | 0.88 | SYK (0.71) | SYKCD63JAK2 | |
| SCHEMBL16848702 | 0.81 | SYK (0.81) | SYKCD63JAK2 | |
| Lanraplenib SCHEMBL16820581 | 0.81 | SYK (1.00) | SYKCD63JAK2 | |
| Lanraplenib SCHEMBL29422916 | 0.81 | SYK (1.00) | SYKCD63JAK2 | |
| SCHEMBL16820575 | 0.80 | SYK (1.00) | SYKCD63JAK2 | |
| SCHEMBL15552777 | 0.80 | SYK (1.00) | SYK | |
| SCHEMBL15552055 | 0.78 | SYK (1.00) | SYKCD63JAK2 | |
| SCHEMBL15551877 | 0.78 | SYK (0.57) | SYKCD63JAK2 | |
| SCHEMBL15551875 | 0.78 | SYK (0.57) | SYKCD63JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112939983-A | Synthesis method of SYK kinase inhibitor Lanraplenib | 暨明医药科技（苏州）有限公司 | 2021-06-11 | — | — | CN | claimed |
| CN-112939983-A | Synthesis method of SYK kinase inhibitor Lanraplenib | 暨明医药科技（苏州）有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-112939983-A | Synthesis method of SYK kinase inhibitor Lanraplenib | 暨明医药科技（苏州）有限公司 | 2021-06-11 | — | — | CN | disclosed |