Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028988 | 0.84 | STAT3 (0.54) | STAT3ALDH1A1LMNABACE1RAB9A | |
| SCHEMBL1028987 | 0.84 | STAT3 (0.54) | STAT3ALDH1A1LMNABACE1RAB9A | |
| SCHEMBL28571803 | 0.82 | BACE1 (0.50) | STAT3ALDH1A1LMNABACE1RAB9A | |
| SCHEMBL28573768 | 0.82 | MAPT (0.59) | ALDH1A1LMNABACE1RAB9AKMT2A | |
| SCHEMBL12226830 | 0.81 | STAT3 (0.74) | STAT3ALDH1A1LMNARAB9AEGFR | |
| SCHEMBL4688054 | 0.81 | STAT3 (0.74) | STAT3ALDH1A1LMNARAB9AEGFR | |
| SCHEMBL4688056 | 0.81 | STAT3 (0.74) | STAT3ALDH1A1LMNARAB9AEGFR | |
| SCHEMBL4882206 | 0.81 | TSHR (0.52) | STAT3ALDH1A1LMNARAB9A | |
| SCHEMBL3166353 | 0.81 | TSHR (0.52) | STAT3ALDH1A1LMNARAB9A | |
| SCHEMBL3725269 | 0.80 | CREBBP (0.48) | ALDH1A1LMNABACE1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863899-B | Synthetic method and application of indoline-2-ketone compound | 中国科学院兰州化学物理研究所 | 2021-05-28 | — | — | CN | disclosed |