Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.68 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.62 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855057 | 0.88 | DPP4 (0.67) | DPP4DPP8DPP9PTGS2HRH1 | |
| SCHEMBL2857150 | 0.86 | DPP4 (0.61) | DPP4DPP8DPP9 | |
| SCHEMBL2850234 | 0.86 | DPP4 (0.67) | DPP4DPP8DPP9PTGS2HRH1 | |
| SCHEMBL2857453 | 0.85 | DPP4 (0.66) | DPP4DPP8DPP9PTGS2HRH1 | |
| SCHEMBL2856645 | 0.83 | DPP4 (0.69) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL2711418 | 0.81 | DPP4 (0.98) | DPP4DPP8DPP9 | |
| SCHEMBL2848177 | 0.80 | DPP4 (0.61) | DPP4DPP8DPP9PTGS2HRH1 | |
| SCHEMBL2860105 | 0.80 | DPP4 (0.76) | DPP4DPP8DPP9PTGS2HRH1 | |
| SCHEMBL2709312 | 0.79 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5960969 | 0.79 | DPP4 (0.98) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790725-B2 | Thiazolidine derivatives and medicinal use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-09-07 | — | — | US | disclosed |