Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 9/20 | 0.62 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28913482 | 0.91 | OPRL1 (0.54) | OPRL1MAPTHDAC3HDAC1HDAC2 | |
| SCHEMBL28572429 | 0.78 | OPRL1 (0.64) | OPRL1HDAC3HDAC1HDAC2P2RX7 | |
| SCHEMBL30127671 | 0.78 | OPRL1 (0.97) | OPRL1 | |
| SCHEMBL23974556 | 0.77 | OPRL1 (1.00) | OPRL1 | |
| SCHEMBL23974682 | 0.75 | OPRL1 (0.61) | OPRL1 | |
| SCHEMBL23974179 | 0.74 | OPRL1 (0.62) | OPRL1IDO1MAPTGSK3B | |
| SCHEMBL28561976 | 0.73 | OPRL1 (0.62) | OPRL1 | |
| SCHEMBL23974362 | 0.73 | OPRL1 (0.65) | OPRL1 | |
| SCHEMBL28555111 | 0.72 | OPRL1 (0.64) | OPRL1HDAC3HDAC1HDAC2 | |
| SCHEMBL28912654 | 0.72 | OPRL1 (0.62) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105605-A | Substituted cyclohexyl compounds as NOP inhibitors | 达特神经科学有限公司 | 2020-12-18 | — | — | CN | disclosed |