Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28518413 | 1.00 | MAPT (0.43) | MAPTHSP90AB1HSP90AA1OGASCN9A | |
| SCHEMBL21528192 | 0.85 | MAPT (0.64) | MAPTHSP90AB1HSP90AA1OGA | |
| SCHEMBL21528022 | 0.85 | MAPT (0.64) | MAPTHSP90AB1HSP90AA1OGA | |
| SCHEMBL21528005 | 0.85 | MAPT (0.64) | MAPTHSP90AB1HSP90AA1OGA | |
| SCHEMBL28516998 | 0.84 | MAPT (0.52) | MAPTHSP90AB1HSP90AA1OGALMNA | |
| SCHEMBL30405241 | 0.84 | MAPT (0.52) | MAPTHSP90AB1HSP90AA1OGALMNA | |
| SCHEMBL30405886 | 0.83 | MAPT (0.45) | MAPTHSP90AB1HSP90AA1LMNA | |
| SCHEMBL30675396 | 0.81 | MAPK1 (0.35) | MAPTHSP90AB1HSP90AA1 | |
| SCHEMBL30404408 | 0.81 | MAPT (0.43) | MAPTHSP90AB1HSP90AA1OGALMNA | |
| SCHEMBL25677943 | 0.81 | SCN9A (0.41) | MAPTHSP90AB1SCN9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916194-A | Methods for delaying, preventing and treating acquired resistance to RAS inhibitors | 锐新医药公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-112771054-A | C40-, C28-and C-32-linked rapamycin analogs as mTOR inhibitors | 锐新医药公司 | 2021-05-07 | — | — | CN | disclosed |