Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.65 |
| ▸ | ITGB6 | P18564 | 18/20 | 0.65 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.65 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.65 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.65 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.65 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21713043 | 0.97 | ITGAV (0.68) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL6879730 | 0.97 | ITGAV (0.68) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL21713114 | 0.93 | ITGAV (0.63) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL28565625 | 0.93 | ITGAV (0.58) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL21713052 | 0.92 | ITGAV (0.68) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL21713048 | 0.92 | ITGAV (0.68) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL21744692 | 0.91 | ITGAV (0.60) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL21713127 | 0.90 | ITGAV (0.70) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL21713124 | 0.90 | ITGAV (0.70) | ITGAVITGB6ITGB3ITGB1ITGA5 | |
| SCHEMBL21776208 | 0.89 | ITGAV (0.66) | ITGAVITGB6ITGB3ITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805284-A | Integrin antagonists | 奥克斯润有限责任公司 | 2021-05-14 | — | — | CN | disclosed |