Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 5/20 | 0.35 |
| ▸ | BCR | P11274 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16566107 | 0.92 | ABL1 (0.36) | KMT2AABL1BCRRPS6KA5MEN1 | |
| SCHEMBL7703222 | 0.80 | ABL1 (0.34) | KMT2AABL1BCRRPS6KA5MEN1 | |
| Hydrochloric Acid SCHEMBL2596286 | 0.79 | ABL1 (0.33) | ABL1BCRRPS6KA5 | |
| SCHEMBL25128539 | 0.77 | ABL1 (0.33) | ABL1BCR | |
| SCHEMBL22279296 | 0.77 | KMT2A (0.33) | KMT2AABL1BCR | |
| SCHEMBL20555325 | 0.77 | KMT2A (0.37) | KMT2ATDP1L3MBTL1AXLRPS6KA5 | |
| SCHEMBL24942753 | 0.76 | KMT2A (0.55) | KMT2ATDP1L3MBTL1AXLRPS6KA5 | |
| SCHEMBL2596088 | 0.76 | ABL1 (0.38) | ABL1BCR | |
| SCHEMBL20555492 | 0.72 | KMT2A (0.35) | KMT2ARPS6KA5 | |
| SCHEMBL4579827 | 0.70 | ABL1 (0.31) | ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108117523-B | Preparation method of halogenated uracil compound | 上海医药工业研究院 | 2021-05-07 | — | — | CN | disclosed |