Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 7/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9993528 | 1.00 | S1PR3 (0.45) | S1PR3S1PR4S1PR2ADRB2ADRB1 | |
| SCHEMBL28565309 | 1.00 | S1PR3 (0.45) | S1PR3S1PR4S1PR2ADRB2ADRB1 | |
| SCHEMBL9993134 | 0.86 | S1PR3 (0.44) | S1PR3S1PR4S1PR2ADRB2ADRB1 | |
| SCHEMBL9990779 | 0.86 | S1PR3 (0.44) | S1PR3S1PR4S1PR2ADRB2ADRB1 | |
| SCHEMBL9990780 | 0.86 | S1PR3 (0.44) | S1PR3S1PR4S1PR2ADRB2ADRB1 | |
| SCHEMBL24714159 | 0.82 | SLC6A2 (0.47) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL28578802 | 0.82 | SLC6A2 (0.47) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL9992346 | 0.82 | SLC6A2 (0.47) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL28574464 | 0.81 | S1PR3 (0.40) | S1PR3S1PR4S1PR2ADRB2ADRB1 | |
| SCHEMBL28571545 | 0.81 | S1PR3 (0.40) | S1PR3S1PR4S1PR2ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153014-B | Piperidinone derivatives as MDM2 inhibitors for the treatment of cancer | 安姆根有限公司 | 2021-06-01 | — | — | CN | disclosed |