Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 5/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28912254 | 1.00 | SCN1A (0.39) | SCN1ASCN8ASLC6A2SLC6A4SCN9A | |
| SCHEMBL28549396 | 0.91 | SCN1A (0.36) | SCN1ASCN8ASLC6A2SLC6A4SCN9A | |
| SCHEMBL28563148 | 0.91 | SCN1A (0.36) | SCN1ASCN8ASLC6A2SLC6A4SCN9A | |
| SCHEMBL19614083 | 0.88 | SCN8A (0.39) | SCN1ASCN8ASLC6A2SLC6A4SCN9A | |
| SCHEMBL28564580 | 0.83 | SCN1A (0.36) | SCN1ASCN8ACHEK1 | |
| SCHEMBL19613584 | 0.82 | SCN1A (0.43) | SCN1ASCN8A | |
| SCHEMBL19613879 | 0.82 | SCN1A (0.43) | SCN1ASCN8A | |
| SCHEMBL28556833 | 0.82 | SCN8A (0.63) | SCN1ASCN8A | |
| SCHEMBL19613583 | 0.81 | SCN1A (0.36) | SCN1ASCN8ASLC6A4 | |
| SCHEMBL28559498 | 0.81 | SCN8A (0.37) | SCN1ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638898-B | Heteroaryl substituted sulfonamide compounds and their use as sodium channel inhibitors | 泽农医药公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-112638898-A | Heteroaryl substituted sulfonamide compounds and their use as sodium channel inhibitors | 泽农医药公司 | 2021-04-09 | — | — | CN | disclosed |