⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856716 | 1.00 | — | — | |
| SCHEMBL1960558 | 1.00 | — | — | |
| SCHEMBL3394884 | 0.79 | — | — | |
| SCHEMBL7993176 | 0.79 | — | — | |
| SCHEMBL9505140 | 0.77 | — | — | |
| SCHEMBL12831741 | 0.77 | — | — | |
| SCHEMBL19451627 | 0.77 | — | — | |
| SCHEMBL248833 | 0.73 | — | — | |
| SCHEMBL10717619 | 0.73 | — | — | |
| SCHEMBL250153 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626076-B2 | Process for the synthesis of dimethyl fumarate | BIOPHORE INDIA PHARMAEUTICALS PVT. LTD. (IN) | 2020-04-21 | — | — | US | claimed |
| EP-0541966-A2 | Process for preparing amide derivatives from halomines and acid halides | AMERICAN CYANAMID COMPANY (US) | 1993-05-19 | — | — | EP | claimed |
| US-4299911-A | POLYMER CONTAINING AN ETHYLENICALLY UNSATURATED DOUBLE BOND | SOMAR MANUFACTURING CO., LTD. (JP) | 1981-11-10 | — | — | US | claimed |
| EP-4230264-B1 | PRODRUGS OF FUMARATES AND THEIR USE IN TREATING VARIOUS DESEASES | ALKERMES PHARMA IRELAND LTD (IE) | 2026-01-28 | — | — | EP | disclosed |
| US-20260001890-A1 | Prodrugs of Fumarates and Their Use in Treating Various Diseases | ALKERMES PHARMA IRELAND LTD (IE) | 2026-01-01 | — | — | US | disclosed |
| EP-2970101-B2 | PRODRUGS OF FUMARATES AND THEIR USE IN TREATING VARIOUS DESEASES | ALKERMES PHARMA IRELAND LTD (IE) | 2025-09-03 | — | — | EP | disclosed |
| US-20250127747-A1 | Prodrugs of Fumarates and Their Use in Treating Various Diseases | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2025-04-24 | — | — | US | disclosed |
| US-20250057770-A1 | Monomethylfumarate Prodrug Compositions | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2025-02-20 | — | — | US | disclosed |
| US-20240300969-A1 | Prodrugs of Fumarates and Their Use in Treating Various Diseases | ALKERMES PHARMA IRELAND LTD (IE) | 2024-09-12 | — | — | US | disclosed |
| US-12076306-B2 | Prodrugs of fumarates and their use in treating various diseases | ALKERMES PHARMA IRELAND LIMITED (IE) | 2024-09-03 | — | — | US | disclosed |
| US-11905298-B2 | Prodrugs of fumarates and their use in treating various diseases | ALKERMES PHARMA IRELAND LIMITED (IE) | 2024-02-20 | — | — | US | disclosed |
| EP-2186819-A1 | Novel glucopyranose esters and glucofuranose esters of alkyl- fumarates and their pharmaceutical use | Aditech Pharma AG (CH) | 2010-05-19 | — | — | EP | disclosed |
| EP-1915387-B1 | NOVEL GLUCOPYRANOSE ESTERS AND GLUCOFURANOSE ESTERS OF ALKYL- FUMARATES AND THEIR PHARMACEUTICAL USE | ADITECH PHARMA AG (CH) | 2010-01-20 | — | — | EP | disclosed |
| EP-1915387-A1 | NOVEL GLUCOPYRANOSE ESTERS AND GLUCOFURANOSE ESTERS OF ALKYL- FUMARATES AND THEIR PHARMACEUTICAL USE | Aditech Pharma AB (SE) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007006308-A1 | NOVEL GLUCOPYRANOSE ESTERS AND GLUCOFURANOSE ESTERS OF ALKYL- FU MARATES AND THEIR PHARMACEUTICAL USE | ADITECH PHARMA AB (SE) | 2007-01-18 | — | — | WO | disclosed |
| EP-0735056-B1 | Catalyst for the polymerization of olefines and processes for the polymerization of olefines using the same | TONEN CORP (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5747595-A | TRIALKOXYALKYLSILANE | TONEN CORPORATION (JP) | 1998-05-05 | — | — | US | disclosed |
| EP-0735056-A1 | Catalyst for the polymerization of olefines and processes for the polymerization of olefines using the same | Tonen Corporation (JP) | 1996-10-02 | — | — | EP | disclosed |
| EP-0541966-A2 | Process for preparing amide derivatives from halomines and acid halides | AMERICAN CYANAMID COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| US-4299911-A | POLYMER CONTAINING AN ETHYLENICALLY UNSATURATED DOUBLE BOND | SOMAR MANUFACTURING CO., LTD. (JP) | 1981-11-10 | — | — | US | disclosed |