Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16522624 | 0.94 | BTK (0.49) | PDE10ABTKJAK3DPP4MAP4K4 | |
| SCHEMBL14801041 | 0.91 | CKS1B (0.40) | PDE10ACTSKCKS1BSKP1SKP2 | |
| SCHEMBL14800474 | 0.91 | CKS1B (0.39) | PDE10ACTSKCKS1BSKP1SKP2 | |
| SCHEMBL16522623 | 0.90 | CKS1B (0.46) | PDE10ACKS1BSKP1SKP2BTK | |
| SCHEMBL14800564 | 0.90 | CKS1B (0.39) | PDE10ACTSKCKS1BSKP1SKP2 | |
| SCHEMBL14800700 | 0.88 | CKS1B (0.40) | PDE10ACTSKCKS1BSKP1SKP2 | |
| SCHEMBL14801270 | 0.88 | CKS1B (0.40) | PDE10ACTSKCKS1BSKP1SKP2 | |
| SCHEMBL14801390 | 0.88 | CKS1B (0.40) | PDE10ACTSKCKS1BSKP1SKP2 | |
| SCHEMBL14800510 | 0.88 | CKS1B (0.40) | PDE10ACTSKCKS1BSKP1SKP2 | |
| SCHEMBL14802960 | 0.87 | CKS1B (0.39) | PDE10ACTSKCKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108373476-B | Kinase inhibitor and preparation and application thereof | 成都地奥制药集团有限公司 | 2021-06-01 | — | — | CN | disclosed |