Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11813050 | 0.88 | MEN1 (0.50) | AKR1B1POLBMAPK1HIF1ATSHR | |
| SCHEMBL2228729 | 0.85 | POLB (0.49) | AKR1B1POLBMAPK1HIF1ATSHR | |
| SCHEMBL1741412 | 0.85 | POLB (0.49) | AKR1B1POLBMAPK1HIF1ATSHR | |
| SCHEMBL9049542 | 0.84 | NAALAD2 (0.48) | AKR1B1POLBMAPK1HIF1ATSHR | |
| SCHEMBL6234672 | 0.83 | POLB (0.61) | POLBMAPK1HIF1ATSHRCYP2D6 | |
| SCHEMBL7760516 | 0.83 | HIF1A (0.46) | HIF1ATSHRCYP2D6GAAMAPT | |
| SCHEMBL2878055 | 0.83 | POLB (0.47) | AKR1B1POLBMAPK1HIF1ATSHR | |
| SCHEMBL2878063 | 0.83 | POLB (0.47) | AKR1B1POLBMAPK1HIF1ATSHR | |
| SCHEMBL31267566 | 0.80 | GAA (0.62) | POLBGAAMAPTMME | |
| SCHEMBL60484 | 0.80 | GAA (0.62) | POLBGAAMAPTMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898168-B | Salt of 2-hydroxybenzylamine-succinic acid and preparation method thereof | 天津大学 | 2022-11-11 | — | — | CN | claimed |
| CN-112898168-A | Salt of 2-hydroxybenzylamine-succinic acid and preparation method thereof | 天津大学 | 2021-06-04 | — | — | CN | claimed |
| CN-112898168-B | Salt of 2-hydroxybenzylamine-succinic acid and preparation method thereof | 天津大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-112898168-B | Salt of 2-hydroxybenzylamine-succinic acid and preparation method thereof | 天津大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-112898168-B | Salt of 2-hydroxybenzylamine-succinic acid and preparation method thereof | 天津大学 | 2022-11-11 | — | — | CN | disclosed |
| CN-112898168-A | Salt of 2-hydroxybenzylamine-succinic acid and preparation method thereof | 天津大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-112898168-A | Salt of 2-hydroxybenzylamine-succinic acid and preparation method thereof | 天津大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-112898168-A | Salt of 2-hydroxybenzylamine-succinic acid and preparation method thereof | 天津大学 | 2021-06-04 | — | — | CN | disclosed |