Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 5/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28567425 | 1.00 | CA1 (0.43) | CA1CA2ACHERORCCTSL | |
| SCHEMBL20722877 | 0.92 | CA1 (0.46) | CA1CA2ACHERORCCTSL | |
| SCHEMBL20722500 | 0.90 | MAP4K4 (0.36) | PDE10ACKS1BSKP1SKP2 | |
| SCHEMBL28567921 | 0.88 | CA1 (0.45) | CA1CA2ACHERORCCTSL | |
| SCHEMBL28567919 | 0.88 | CA1 (0.45) | CA1CA2ACHERORCCTSL | |
| SCHEMBL30968500 | 0.88 | CA1 (0.45) | CA1CA2ACHERORCCTSL | |
| SCHEMBL20722776 | 0.88 | CA1 (0.45) | CA1CA2ACHERORCCTSL | |
| SCHEMBL23938263 | 0.85 | CA1 (0.44) | CA1CA2ACHERORCCTSL | |
| SCHEMBL30968421 | 0.85 | CA1 (0.44) | CA1CA2ACHERORCCTSL | |
| SCHEMBL28572866 | 0.85 | CA1 (0.44) | CA1CA2ACHERORCCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-112867712-A | Carboxamides as ubiquitin-specific protease inhibitors | 瓦洛早期发现股份有限公司 | 2021-05-28 | — | — | CN | disclosed |