Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 15/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.45 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28567644 | 1.00 | PIK3CD (0.58) | PIK3CDPIK3CBPIK3CAPIK3CGSMN1; SMN2 | |
| SCHEMBL15812937 | 0.88 | PIK3CD (0.64) | PIK3CDPIK3CBPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL15812935 | 0.88 | PIK3CD (0.64) | PIK3CDPIK3CBPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL356153 | 0.88 | PIK3CG (0.58) | PIK3CDPIK3CBPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL21847966 | 0.88 | PIK3CG (0.58) | PIK3CDPIK3CBPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL356152 | 0.88 | PIK3CG (0.58) | PIK3CDPIK3CBPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL16292921 | 0.87 | PIK3CD (0.60) | PIK3CDPIK3CBPIK3CAPIK3CGSMN1; SMN2 | |
| SCHEMBL16292920 | 0.87 | PIK3CD (0.60) | PIK3CDPIK3CBPIK3CAPIK3CGSMN1; SMN2 | |
| SCHEMBL15816551 | 0.85 | PIK3CG (0.51) | PIK3CDPIK3CBPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL15816549 | 0.85 | PIK3CG (0.51) | PIK3CDPIK3CBPIK3CAPIK3CGPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107690433-B | Heteroaryl derivative or pharmaceutically acceptable salt thereof, preparation method thereof, and pharmaceutical composition for preventing or treating PI3 kinase-associated diseases comprising the same as active ingredient | 韩国化学研究院 | 2021-04-09 | — | — | CN | disclosed |