Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 7/20 | 0.67 |
| ▸ | AURKA | O14965 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29408530 | 0.99 | PDE5A (0.66) | PDE5AAURKAALDH1A1MAPTKDM4E | |
| SCHEMBL291205 | 0.92 | PDE5A (0.56) | PDE5AAURKAHRH4 | |
| SCHEMBL29408486 | 0.92 | PDE5A (0.80) | PDE5AAURKAALDH1A1MAPTKDM4E | |
| SCHEMBL28567163 | 0.92 | PDE5A (0.80) | PDE5AAURKAALDH1A1MAPTKDM4E | |
| SCHEMBL28570855 | 0.91 | PDE5A (0.72) | PDE5AAURKAALDH1A1MAPTKDM4E | |
| SCHEMBL29408531 | 0.91 | PDE5A (0.72) | PDE5AAURKAALDH1A1MAPTKDM4E | |
| SCHEMBL6068361 | 0.90 | PDE5A (0.68) | PDE5AAURKAALDH1A1MAPTKDM4E | |
| SCHEMBL6068273 | 0.89 | PDE5A (0.66) | PDE5AAURKAALDH1A1MAPTKDM4E | |
| SCHEMBL5522573 | 0.89 | PDE5A (0.74) | PDE5AAURKAALDH1A1MAPTKDM4E | |
| SCHEMBL6068325 | 0.89 | PDE5A (0.62) | PDE5AAURKAALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114984229-A | Treatment of addiction and impulse control disorders using PDE7 inhibitors | 奥默罗斯公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-112168972-A | Treatment of addiction and impulse control disorders using PDE7 inhibitors | 奥默罗斯公司 | 2021-01-05 | — | — | CN | disclosed |