Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 4/20 | 0.67 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.67 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28562492 | 0.93 | VEGFA (0.68) | VEGFAEGLN1PLA2G7MGLLABHD6 | |
| SCHEMBL17005964 | 0.89 | VEGFA (0.52) | VEGFAEGLN1PLA2G7MGLLABHD6 | |
| SCHEMBL28569013 | 0.89 | VEGFA (0.69) | VEGFAEGLN1MMP1MMP9MMP13 | |
| SCHEMBL17005963 | 0.89 | VEGFA (0.52) | VEGFAEGLN1LMNAGFERKDM4E | |
| SCHEMBL28567361 | 0.87 | VEGFA (0.83) | VEGFAEGLN1MMP1MMP9MMP13 | |
| SCHEMBL28563655 | 0.87 | VEGFA (0.75) | VEGFAEGLN1PLA2G7MGLLABHD6 | |
| SCHEMBL28582330 | 0.86 | VEGFA (0.72) | VEGFAEGLN1MMP1MMP9MMP13 | |
| SCHEMBL17005920 | 0.85 | VEGFA (0.53) | VEGFAEGLN1LMNAFAAHGFER | |
| SCHEMBL28571955 | 0.85 | VEGFA (0.67) | VEGFAEGLN1MMP1MMP9MMP13 | |
| SCHEMBL28914231 | 0.85 | VEGFA (0.76) | VEGFAEGLN1MMP1MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232120-B | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2- (1H) -ones | 爱尔皮奥治疗有限公司 | 2021-01-08 | — | — | CN | disclosed |