Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MECP2 | P51608 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29894627 | 1.00 | MAPT (0.64) | MAPTLMNAHPGDTSHRMEN1 | |
| SCHEMBL29894470 | 0.83 | POLB (0.73) | MAPTLMNAMEN1KMT2APOLB | |
| SCHEMBL21565076 | 0.83 | POLB (0.73) | MAPTLMNAMEN1KMT2APOLB | |
| SCHEMBL28561573 | 0.80 | POLB (0.64) | MAPTLMNAHPGDTSHRMEN1 | |
| SCHEMBL8785242 | 0.80 | POLB (0.60) | MAPTLMNAHPGDTSHRMEN1 | |
| SCHEMBL9464627 | 0.79 | POLB (0.88) | MAPTLMNAHPGDTSHRMEN1 | |
| SCHEMBL17754981 | 0.79 | KMT2A (0.63) | MAPTLMNAHPGDTSHRMEN1 | |
| Hydrochloric Acid SCHEMBL8781797 | 0.79 | POLB (0.59) | MAPTLMNAHPGDTSHRMEN1 | |
| SCHEMBL17755037 | 0.78 | MAPT (0.61) | MAPTLMNAHPGDTSHRMEN1 | |
| SCHEMBL30733281 | 0.78 | MAPT (0.72) | MAPTLMNAHPGDTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112679426-B | Intermediate compound for synthesizing nitrogen-containing heterocycle and preparation method and application thereof | 上海交通大学 | 2022-09-30 | — | — | CN | disclosed |
| CN-112679426-A | Intermediate compound for synthesis of nitrogen-containing heterocycle and preparation method and application thereof | 上海交通大学 | 2021-04-20 | — | — | CN | disclosed |