Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 17/20 | 0.69 |
| ▸ | VEGFA | P15692 | 6/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16555808 | 0.88 | EPAS1 (0.70) | EPAS1VEGFA | |
| SCHEMBL18036803 | 0.82 | EPAS1 (0.66) | EPAS1VEGFA | |
| SCHEMBL18036772 | 0.82 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16560947 | 0.82 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL21005478 | 0.82 | EPAS1 (0.66) | EPAS1VEGFA | |
| SCHEMBL21004989 | 0.81 | EPAS1 (0.65) | EPAS1VEGFA | |
| SCHEMBL21005003 | 0.81 | EPAS1 (0.65) | EPAS1VEGFA | |
| SCHEMBL21572938 | 0.80 | VEGFA (0.64) | EPAS1VEGFA | |
| SCHEMBL16560920 | 0.79 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL21005035 | 0.79 | VEGFA (0.62) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776607-B | Aryl phosphorus oxygen and aryl phosphorus sulfur compounds, and preparation method and application thereof | 青岛海洋生物医药研究院 | 2021-06-04 | — | — | CN | disclosed |