SCHEMBL28568575

SCHEMBL28568575

CC(=O)CC(C)=Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.56
AKR1C3 P42330 1/20 0.55
MTNR1A P48039 2/20 0.50
MTNR1B P49286 2/20 0.50
ALDH1A1 P00352 2/20 0.50
TSHR P16473 1/20 0.50
GRIK1 P39086 1/20 0.49
GRIK2 Q13002 1/20 0.49
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
HTT P42858 1/20 0.46
FBP1 P09467 1/20 0.46
GLA P06280 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
KDM4E B2RXH2 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylenediamine SCHEMBL28437824 0.93 RECQL (0.50) RECQLAKR1C3MTNR1AMTNR1BALDH1A1
SCHEMBL2910667 0.88 RECQL (0.67) RECQLAKR1C3MTNR1AMTNR1BALDH1A1
SCHEMBL11310912 0.88 RECQL (0.67) RECQLAKR1C3MTNR1AMTNR1BALDH1A1
SCHEMBL2910666 0.88 RECQL (0.67) RECQLAKR1C3MTNR1AMTNR1BALDH1A1
Hydrochloric Acid SCHEMBL11747959 0.86 RECQL (0.65) RECQLAKR1C3MTNR1AMTNR1BALDH1A1
SCHEMBL309268 0.84 RECQL (0.53) RECQLAKR1C3MTNR1AMTNR1BALDH1A1
SCHEMBL309269 0.84 RECQL (0.53) RECQLAKR1C3MTNR1AMTNR1BALDH1A1
SCHEMBL11861086 0.84 AKR1C3 (0.57) RECQLAKR1C3MTNR1AMTNR1BALDH1A1
SCHEMBL5678234 0.84 RECQL (0.53) RECQLAKR1C3MTNR1AMTNR1BALDH1A1
SCHEMBL11747945 0.84 RECQL (0.53) RECQLAKR1C3MTNR1AMTNR1BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110183320-B Polyene diketone antitumor compound 四川大学 2021-06-11 CN disclosed