Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11907198 | 0.91 | NPC1 (0.42) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL30129926 | 0.91 | NPC1 (0.42) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL10654837 | 0.86 | NPC1 (0.49) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28915334 | 0.83 | NPC1 (0.42) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28138210 | 0.83 | MAPT (0.39) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28289452 | 0.83 | NPC1 (0.42) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28138208 | 0.83 | MAOB (0.38) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28574627 | 0.83 | NPC1 (0.41) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28861329 | 0.80 | NPC1 (0.57) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28583384 | 0.80 | PRF1 (0.39) | MAPTNPC1RAB9AKDM4EMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112941549-A | Synthetic method of quinazoline derivative, benzoxazine derivative and benzothiazole derivative | 石河子大学 | 2021-06-11 | — | — | CN | disclosed |