Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2849736 | 0.95 | DPP4 (0.49) | DPP4DPP8DPP9RORCHTR1A | |
| SCHEMBL2708189 | 0.93 | DPP4 (0.51) | DPP4DPP8DPP9HTR1ATGM2 | |
| SCHEMBL2856739 | 0.92 | DPP4 (0.50) | DPP4DPP8DPP9HTR1ATGM2 | |
| SCHEMBL2860543 | 0.91 | DPP4 (0.49) | DPP4DPP8DPP9HTR1ATGM2 | |
| SCHEMBL2709330 | 0.91 | DPP4 (0.52) | DPP4DPP8DPP9TGM2 | |
| SCHEMBL2709329 | 0.90 | DPP4 (0.52) | DPP4DPP8DPP9TGM2 | |
| SCHEMBL2855142 | 0.90 | DPP4 (0.52) | DPP4DPP8DPP9HTR1ATGM2 | |
| SCHEMBL2707892 | 0.90 | DPP4 (0.52) | DPP4DPP8DPP9TGM2 | |
| SCHEMBL2710990 | 0.89 | DPP4 (0.51) | DPP4DPP8DPP9TGM2 | |
| SCHEMBL2709325 | 0.86 | DPP4 (0.65) | DPP4DPP8DPP9DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790725-B2 | Thiazolidine derivatives and medicinal use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-09-07 | — | — | US | disclosed |