Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | P2RX1 | P51575 | 6/20 | 0.57 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.57 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.57 |
| ▸ | TMPRSS4 | Q9NRS4 | 3/20 | 0.57 |
| ▸ | KDR | P35968 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | CHUK | O15111 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MYLK | Q15746 | 1/20 | 0.51 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.51 |
| ▸ | JUN | P05412 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4348880 | 0.87 | EPHX2 (0.69) | MAPTP2RX1P2RX7P2RX4TMPRSS4 | |
| SCHEMBL3692790 | 0.86 | KDR (0.73) | MAPTP2RX1P2RX7P2RX4TMPRSS4 | |
| SCHEMBL2681462 | 0.86 | MAPT (0.78) | MAPTP2RX1P2RX7P2RX4KDR | |
| SCHEMBL6567241 | 0.84 | EPHX1 (0.59) | MAPTCA2CA9MEN1KMT2A | |
| SCHEMBL3681047 | 0.83 | CHRNA7 (0.67) | MAPTKDRCA12CA1CA2 | |
| SCHEMBL11007470 | 0.81 | KDR (0.58) | MAPTP2RX1P2RX7P2RX4TMPRSS4 | |
| SCHEMBL11001119 | 0.81 | MAPT (0.57) | MAPTP2RX1P2RX7P2RX4TMPRSS4 | |
| SCHEMBL8172368 | 0.80 | CA12 (0.64) | MAPTP2RX1P2RX7P2RX4TMPRSS4 | |
| SCHEMBL11002386 | 0.78 | KDR (0.82) | KDRCA1CA2CA9 | |
| SCHEMBL16628060 | 0.78 | CA12 (0.66) | MAPTP2RX1P2RX7P2RX4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759564-B | Diaryl urea compound and its prepn and medicinal use | 中国医学科学院药物研究所 | 2023-09-26 | — | — | CN | disclosed |
| CN-112759564-A | Diaryl urea compound and its preparation method and medicinal use | 中国医学科学院药物研究所 | 2021-05-07 | — | — | CN | disclosed |