Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Butylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CD81 | P60033 | 1/20 | 0.30 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262847 | 0.87 | EP300 (0.43) | EP300DNM1GRIK1LSSEPHX2 | |
| SCHEMBL6082010 | 0.87 | EP300 (0.43) | EP300DNM1GRIK1LSSEPHX2 | |
| Bromide SCHEMBL1061720 | 0.85 | CD81 (0.37) | CD81TDP1 | |
| SCHEMBL22600 | 0.83 | CD81 (0.38) | CD81TDP1 | |
| SCHEMBL30875818 | 0.83 | CD81 (0.38) | CD81TDP1 | |
| SCHEMBL112617 | 0.83 | CD81 (0.38) | CD81TDP1 | |
| SCHEMBL2202388 | 0.83 | EP300 (0.40) | EP300DNM1GRIK1LSSEPHX2 | |
| SCHEMBL9436708 | 0.81 | EP300 (0.42) | EP300DNM1LSSEPHX2 | |
| SCHEMBL8762016 | 0.81 | EP300 (0.42) | EP300DNM1LSSEPHX2 | |
| Hydrochloric Acid SCHEMBL966904 | 0.81 | CD81 (0.37) | CD81 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112870990-B | Antibacterial and pollution-resistant reverse osmosis composite membrane and preparation method thereof | 中化(宁波)润沃膜科技有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-112870990-A | Antibacterial and pollution-resistant reverse osmosis composite membrane and preparation method thereof | 中化(宁波)润沃膜科技有限公司 | 2021-06-01 | — | — | CN | disclosed |