Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30639135 | 0.81 | SMN1; SMN2 (0.53) | KDM4EMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL22435548 | 0.80 | KDM4E (0.59) | KDM4EMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL31230012 | 0.80 | KDM4E (0.59) | KDM4EMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL12480983 | 0.78 | GAA (0.49) | KDM4EMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL28088687 | 0.75 | MAPT (0.40) | KDM4EMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL4845139 | 0.70 | MAPT (0.50) | KDM4EMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL4906578 | 0.69 | KMT2A (0.61) | KDM4EMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL21001348 | 0.69 | SMN1; SMN2 (0.50) | KDM4EMAPTLMNAALDH1A1KMT2A | |
| SCHEMBL4847871 | 0.68 | CLK1 (0.51) | KDM4EMAPTLMNAALDH1A1POLB | |
| SCHEMBL12481396 | 0.68 | GAA (0.50) | KDM4EMAPTLMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107200741-B | Preparation method of anaplastic lymphoma kinase inhibitor | 首药控股(北京)有限公司 | 2021-06-08 | — | — | CN | disclosed |