SCHEMBL28570936

SCHEMBL28570936

N=C=O.N=C=O.O=C=Nc1cccc(N=C=O)c1N=C=O

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.56
GABRA1 P14867 1/20 0.47
GABRB2 P47870 1/20 0.47
TRPA1 O75762 1/20 0.35
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL109280 0.93 CYP3A4 (0.62) CYP3A4GABRA1GABRB2TRPA1ALDH1A1
SCHEMBL1669008 0.86 CYP3A4 (0.57) CYP3A4GABRA1GABRB2TRPA1ALDH1A1
SCHEMBL28953537 0.86 CYP3A4 (0.57) CYP3A4GABRA1GABRB2TRPA1ALDH1A1
SCHEMBL9445659 0.83 CYP3A4 (0.56) CYP3A4GABRA1GABRB2TRPA1ALDH1A1
SCHEMBL28831497 0.82 CYP3A4 (0.56) CYP3A4GABRA1GABRB2TRPA1ALDH1A1
SCHEMBL28583292 0.80 CYP3A4 (0.87) CYP3A4GABRA1GABRB2TRPA1ALDH1A1
SCHEMBL17007517 0.80 CYP3A4 (0.54) CYP3A4GABRA1GABRB2TRPA1ALDH1A1
SCHEMBL5456903 0.80 CYP3A4 (0.54) CYP3A4GABRA1GABRB2TRPA1ALDH1A1
SCHEMBL462306 0.78 CYP3A4 (0.52) CYP3A4GABRA1GABRB2TRPA1ALDH1A1
SCHEMBL30520271 0.78 CYP3A4 (0.63) CYP3A4GABRA1GABRB2TRPA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109575216-B Polythiol composition for plastic optical lens SKC株式会社 2021-05-11 CN disclosed