⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL285719 | 1.00 | — | — | |
| SCHEMBL28387843 | 0.85 | — | — | |
| SCHEMBL8600060 | 0.83 | CA1 (0.43) | — | |
| SCHEMBL10496302 | 0.81 | CA1 (0.42) | — | |
| SCHEMBL10496299 | 0.81 | CA1 (0.42) | — | |
| SCHEMBL10496296 | 0.81 | CA1 (0.42) | — | |
| SCHEMBL15288442 | 0.81 | CA1 (0.42) | — | |
| SCHEMBL10496304 | 0.81 | CA1 (0.42) | — | |
| SCHEMBL15288444 | 0.81 | CA1 (0.42) | — | |
| SCHEMBL28823662 | 0.81 | CA1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5412006-A | Electrorheological cels and a method for the preparation thereof | DOW CORNING CORPORATION (US) | 1995-05-02 | — | — | US | claimed |
| EP-2427457-B1 | ISOXAZOLE-PYRIDINE DERIVATIVES AS GABA MODULATORS | HOFFMANN LA ROCHE (CH) | 2013-07-17 | — | — | EP | disclosed |
| EP-2427457-A1 | ISOXAZOLE-PYRIDINE DERIVATIVES AS GABA MODULATORS | F. Hoffmann-La Roche AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010127978-A1 | ISOXAZOLE-PYRIDINE DERIVATIVES AS GABA MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-11-11 | — | — | WO | disclosed |
| EP-0799860-B1 | Method for enhancing longevity of a surface drying oil on a silicone composition modified by incorporation of zinc oxide | DOW CORNING (US) | 1999-10-13 | — | — | EP | disclosed |
| EP-0672745-B1 | Electrorheological gels and method for preparation | DOW CORNING (US) | 1998-02-25 | — | — | EP | disclosed |
| EP-0491335-B1 | Method for preparing oximosilane-functional vinylic copolymers | DOW CORNING (US) | 1996-01-10 | — | — | EP | disclosed |
| EP-0672745-A2 | Electrorheological gels and method for preparation | DOW CORNING CORPORATION (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5412006-A | Electrorheological cels and a method for the preparation thereof | DOW CORNING CORPORATION (US) | 1995-05-02 | — | — | US | disclosed |
| CN-1024416-C | Process for preparing amino-urethanes and their use | HOECHST AG (DE) | 1994-05-04 | — | — | CN | disclosed |
| US-5145912-A | Curing with dialkyl ketoxime, coatings | DOW CORNING CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| EP-0491335-A1 | Method for preparing oximosilane-functional vinylic copolymers | DOW CORNING CORPORATION (US) | 1992-06-24 | — | — | EP | disclosed |
| EP-0373420-A1 | Process for the separation of copper from aqueous basic solutions | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-20 | — | — | EP | disclosed |
| CN-87100667-A | Process for preparing amino-carbamates and their use | — | 1987-08-26 | — | — | CN | disclosed |