Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.84 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2852409 | 0.91 | DPP4 (0.83) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL2857345 | 0.91 | DPP4 (0.98) | DPP4PTGS2HRH1KCNH2DPP8 | |
| Hydrochloric Acid SCHEMBL2708782 | 0.90 | DPP4 (0.79) | DPP4PTGS2HRH1KCNH2DPP8 | |
| SCHEMBL2850472 | 0.85 | DPP4 (0.82) | DPP4PTGS2HRH1KCNH2DPP8 | |
| SCHEMBL2861930 | 0.83 | DPP4 (0.79) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL2708397 | 0.82 | DPP4 (0.79) | DPP4 | |
| SCHEMBL2852515 | 0.80 | DPP4 (0.73) | DPP4PTGS2HRH1KCNH2DPP8 | |
| SCHEMBL2856719 | 0.78 | DPP4 (0.75) | DPP4PTGS2HRH1KCNH2DPP8 | |
| SCHEMBL2856814 | 0.77 | DPP4 (0.87) | DPP4PTGS2HRH1KCNH2DPP8 | |
| Hydrochloric Acid SCHEMBL2709870 | 0.76 | DPP4 (0.98) | DPP4PTGS2HRH1KCNH2DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790725-B2 | Thiazolidine derivatives and medicinal use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-09-07 | — | — | US | disclosed |