Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 5/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30180434 | 1.00 | CCR9 (0.49) | CCR9DRD2DRD4CNR1CCR2 | |
| SCHEMBL28575217 | 1.00 | CCR9 (0.49) | CCR9DRD2DRD4CNR1CCR2 | |
| SCHEMBL30180480 | 0.92 | F10 (0.43) | CCR9DRD2CNR1CCR2F10 | |
| SCHEMBL28580755 | 0.92 | F10 (0.43) | CCR9DRD2CNR1CCR2F10 | |
| SCHEMBL28580754 | 0.92 | F10 (0.43) | CCR9DRD2CNR1CCR2F10 | |
| SCHEMBL28573653 | 0.89 | CCR9 (0.54) | CCR9DRD2CNR1F10PRKAA2 | |
| SCHEMBL28573651 | 0.89 | CCR9 (0.54) | CCR9DRD2CNR1F10PRKAA2 | |
| SCHEMBL31689641 | 0.89 | CCR9 (0.54) | CCR9DRD2CNR1F10PRKAA2 | |
| SCHEMBL28588621 | 0.88 | CCR9 (0.49) | CCR9DRD2CNR1F10PRKAA2 | |
| SCHEMBL28582822 | 0.88 | CCR9 (0.54) | CCR9DRD2DRD4CNR1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |