SCHEMBL28575419

SCHEMBL28575419

CCCCCCCCCCCCOc1c(N)ccc(N)c1OCCCCCCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
NR5A1 Q13285 1/20 0.47
TLR4 O00206 3/20 0.45
ALDH1A1 P00352 2/20 0.45
HSD17B10 Q99714 2/20 0.45
KDM4E B2RXH2 1/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MCHR1 Q99705 1/20 0.42
TLR8 Q9NR97 1/20 0.42
LMNA P02545 2/20 0.42
TP53 P04637 2/20 0.42
GAA P10253 1/20 0.42
ALOX15 P16050 1/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28564551 1.00 TSHR (0.50) TSHRCYP1A2CYP2C9CYP2C19NR5A1
SCHEMBL28471208 0.88 TSHR (0.56) TSHRCYP1A2CYP2C9CYP2C19NR5A1
SCHEMBL10424242 0.83 CYP1A2 (0.49) TSHRCYP1A2CYP2C9CYP2C19NR5A1
SCHEMBL1236256 0.82 CYP1A2 (0.56) TSHRCYP1A2CYP2C9CYP2C19TLR4
SCHEMBL28168438 0.81 CYP1A2 (0.47) TSHRCYP1A2CYP2C9CYP2C19NR5A1
SCHEMBL10690464 0.81 NR5A1 (0.52) TSHRNR5A1TP53LTA4H
SCHEMBL10689444 0.81 NR5A1 (0.52) TSHRNR5A1TP53LTA4H
SCHEMBL10690008 0.81 NR5A1 (0.52) TSHRNR5A1TP53LTA4H
SCHEMBL10693533 0.81 NR5A1 (0.52) TSHRNR5A1TP53LTA4H
SCHEMBL10692048 0.81 NR5A1 (0.52) TSHRNR5A1TP53LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112457866-B Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 深圳清荷科技有限公司 2021-07-27 CN claimed
CN-112877079-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 深圳清荷科技有限公司 2021-06-01 CN claimed
CN-112457866-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 深圳清荷科技有限公司 2021-03-09 CN claimed