Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.93 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.93 |
| ▸ | HRH1 | P35367 | 2/20 | 0.66 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.59 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL18141892 | 1.00 | TDP1 (0.93) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| Bromide SCHEMBL3191407 | 1.00 | TDP1 (0.93) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| Bromide SCHEMBL15822430 | 0.98 | TDP1 (0.96) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| SCHEMBL6114843 | 0.98 | TDP1 (0.96) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| SCHEMBL6115248 | 0.98 | TDP1 (0.96) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| SCHEMBL25380936 | 0.98 | TDP1 (0.96) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| SCHEMBL25382598 | 0.98 | TDP1 (0.96) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| SCHEMBL25381172 | 0.98 | TDP1 (0.96) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| SCHEMBL6114977 | 0.98 | TDP1 (0.96) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 | |
| SCHEMBL25381701 | 0.98 | TDP1 (0.96) | TDP1L3MBTL1HRH1CYP2A6TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724107-B | Preparation method of alpha-oxo-2-furyl acetic acid and ester thereof | 南京工业大学 | 2024-01-30 | — | — | CN | claimed |
| CN-112724107-A | Preparation method of alpha-oxo-2-furyl acetic acid and ester thereof | 南京工业大学 | 2021-04-30 | — | — | CN | claimed |
| CN-120089787-A | Lithium ion battery | 珠海冠宇电池股份有限公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-112724107-A | Preparation method of alpha-oxo-2-furyl acetic acid and ester thereof | 南京工业大学 | 2021-04-30 | — | — | CN | disclosed |