Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.36 |
| ▸ | MET | P08581 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19923138 | 0.74 | MAPK1 (0.37) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL19923177 | 0.71 | CHEK1 (0.38) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL18095757 | 0.70 | GRM2 (0.35) | GRM2PIM1PIM2WNT1GSK3B | |
| SCHEMBL29504545 | 0.68 | IRAK4 (0.50) | PIK3CAGRM2METIRAK4ACVR1B | |
| Hydrochloric Acid SCHEMBL29504483 | 0.67 | IRAK4 (0.49) | PIK3CAGRM2METIRAK4ACVR1B | |
| SCHEMBL19923122 | 0.67 | FYN (0.41) | METIRAK4WNT1GSK3BDYRK1A | |
| SCHEMBL19923211 | 0.67 | CCNC (0.38) | GRM2METWNT1GSK3BDYRK1A | |
| SCHEMBL19923209 | 0.67 | GRM2 (0.37) | GRM2METPIM1PIM2WNT1 | |
| SCHEMBL19923241 | 0.65 | CHEK1 (0.36) | PIK3CAIRAK4PIK3CD | |
| SCHEMBL19923205 | 0.65 | MAPT (0.36) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107667092-B | Formylated N-heterocyclic derivatives as FGFR4 inhibitors | 诺华股份有限公司 | 2021-05-28 | — | — | CN | disclosed |