Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 17/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28576256 | 0.88 | P2RY14 (0.78) | P2RY14SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28566528 | 0.86 | P2RY14 (1.00) | P2RY14 | |
| SCHEMBL28563307 | 0.80 | P2RY14 (0.77) | P2RY14SMN1; SMN2 | |
| SCHEMBL28571458 | 0.77 | P2RY14 (0.87) | P2RY14 | |
| SCHEMBL28572661 | 0.75 | P2RY14 (1.00) | P2RY14 | |
| SCHEMBL28570029 | 0.75 | P2RY14 (0.64) | P2RY14PTGDR2 | |
| SCHEMBL28914475 | 0.72 | P2RY14 (0.70) | P2RY14 | |
| SCHEMBL8512689 | 0.70 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL28577402 | 0.70 | P2RY14 (0.72) | P2RY14 | |
| SCHEMBL28569055 | 0.69 | P2RY14 (0.54) | P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423377-B | 5-amino-1H-pyrazole derivative, preparation method and medical application | 中国药科大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-111423377-A | 5-amino-1H-pyrazole derivative, preparation method and medical application | 中国药科大学 | 2020-07-17 | — | — | CN | disclosed |