Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 12/20 | 0.63 |
| ▸ | MGAM | O43451 | 11/20 | 0.63 |
| ▸ | AMY1A | P0DUB6 | 11/20 | 0.63 |
| ▸ | SI | P14410 | 11/20 | 0.63 |
| ▸ | MGAM2 | Q2M2H8 | 11/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | F2 | P00734 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.63 |
| ▸ | F12 | P00748 | 5/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29502831 | 1.00 | GAA (0.63) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL28594361 | 0.91 | GAA (0.63) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL29502832 | 0.87 | GAA (0.52) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL28916403 | 0.87 | GAA (0.52) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL29502829 | 0.85 | GAA (0.56) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL28583923 | 0.84 | F12 (0.69) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL29502827 | 0.84 | F12 (0.69) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL28915566 | 0.82 | GAA (0.52) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL2493561 | 0.78 | MGAM (1.00) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL29433322 | 0.78 | MGAM (1.00) | GAAMGAMAMY1ASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045508-B | Method for synthesizing diaminoalkene by NBS (N-bromosuccinimide) to promote polarity reversal of enaminone | 河南科技大学 | 2022-04-22 | — | — | CN | disclosed |
| CN-113045508-A | Method for synthesizing diaminoalkene by NBS (N-bromosuccinimide) to promote polarity reversal of enaminone | 河南科技大学 | 2021-06-29 | — | — | CN | disclosed |