Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28914430 | 0.91 | ESR1 (0.49) | KMT2AMEN1TDP1ESR1ESR2 | |
| SCHEMBL28569767 | 0.88 | ESR1 (0.47) | KMT2AMEN1MAPTTDP1LMNA | |
| SCHEMBL28574738 | 0.88 | ESR1 (0.41) | KMT2AMEN1MAPTTDP1ESR1 | |
| SCHEMBL28588102 | 0.88 | KMT2A (0.41) | KMT2AMEN1MAPTTDP1LMNA | |
| SCHEMBL28587202 | 0.87 | KMT2A (0.46) | KMT2AMEN1MAPTTDP1LMNA | |
| SCHEMBL28587204 | 0.87 | KMT2A (0.41) | KMT2AMEN1MAPTTDP1LMNA | |
| SCHEMBL28576070 | 0.86 | KMT2A (0.49) | KMT2AMEN1LMNAESR1ESR2 | |
| SCHEMBL29255686 | 0.86 | KMT2A (0.45) | KMT2AMEN1MAPTTDP1HSD17B10 | |
| SCHEMBL28587207 | 0.85 | PRSS1 (0.39) | KMT2AMEN1MAPTTDP1ESR1 | |
| SCHEMBL29116796 | 0.83 | KMT2A (0.54) | KMT2AMEN1MAPTTDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979470-A | Methyl rupestonic acid derivative containing benzoyl and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2021-06-18 | — | — | CN | disclosed |