Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 14/20 | 0.44 |
| ▸ | PLG | P00747 | 12/20 | 0.44 |
| ▸ | F2 | P00734 | 11/20 | 0.44 |
| ▸ | PLAU | P00749 | 10/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21822243 | 0.90 | ST14 (0.53) | F10ST14PLGF2PLAU | |
| SCHEMBL25017360 | 0.87 | F10 (0.55) | F10ST14PLGF2PLAU | |
| SCHEMBL25016835 | 0.86 | ST14 (0.44) | F10ST14PLGF2PLAU | |
| SCHEMBL25016349 | 0.83 | ST14 (0.45) | F10ST14PLGF2PLAU | |
| SCHEMBL25015872 | 0.83 | F10 (0.51) | F10ST14PLGF2PLAU | |
| SCHEMBL25015878 | 0.83 | F10 (0.44) | F10ST14PLGF2PLAU | |
| SCHEMBL21822622 | 0.80 | PARP14 (0.43) | F10ST14PLGF2PLAU | |
| SCHEMBL21822620 | 0.80 | PARP14 (0.43) | F10ST14PLGF2PLAU | |
| SCHEMBL25015875 | 0.80 | F10 (0.43) | F10ST14PLGF2PLAU | |
| SCHEMBL25016360 | 0.78 | F10 (0.48) | F10ST14PLGF2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |