Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 5/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | USP14 | P54578 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.32 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28580786 | 1.00 | F10 (0.36) | F10DRD2DRD3KDM1AMAOB | |
| SCHEMBL30180691 | 1.00 | F10 (0.36) | F10DRD2DRD3KDM1AMAOB | |
| SCHEMBL30180745 | 0.92 | F10 (0.37) | F10DRD2DRD3KDM1AMAOB | |
| SCHEMBL28588827 | 0.92 | F10 (0.37) | F10DRD2DRD3KDM1AMAOB | |
| SCHEMBL28588823 | 0.92 | F10 (0.37) | F10DRD2DRD3KDM1AMAOB | |
| SCHEMBL25017935 | 0.90 | F10 (0.41) | F10DRD2DRD3KDM1AMAOB | |
| SCHEMBL30180569 | 0.90 | F10 (0.41) | F10DRD2DRD3KDM1AMAOB | |
| SCHEMBL28578367 | 0.90 | F10 (0.41) | F10DRD2DRD3KDM1AMAOB | |
| SCHEMBL28583330 | 0.89 | F10 (0.38) | F10DRD2DRD3KDM1AMAOB | |
| SCHEMBL28583328 | 0.89 | F10 (0.38) | F10DRD2DRD3KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |