Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850489 | 0.93 | TAAR1 (0.53) | TAAR1ALDH1A1TRPV1SMN1; SMN2KMT2A | |
| SCHEMBL2856221 | 0.91 | TAAR1 (0.49) | TAAR1ALDH1A1TRPV1SMN1; SMN2KMT2A | |
| SCHEMBL2853130 | 0.90 | TAAR1 (0.45) | TAAR1ALDH1A1TRPV1SMN1; SMN2KMT2A | |
| SCHEMBL2853284 | 0.90 | IDO1 (0.46) | TAAR1ALDH1A1TRPV1SMN1; SMN2KMT2A | |
| SCHEMBL2857531 | 0.89 | TAAR1 (0.52) | TAAR1ALDH1A1TRPV1SMN1; SMN2KMT2A | |
| SCHEMBL2859081 | 0.88 | TAAR1 (0.45) | TAAR1ALDH1A1TRPV1SMN1; SMN2KMT2A | |
| SCHEMBL2857726 | 0.85 | TRPV1 (0.40) | TAAR1ALDH1A1TRPV1SMN1; SMN2KMT2A | |
| SCHEMBL2855572 | 0.83 | TAAR1 (0.48) | TAAR1ALDH1A1TRPV1SMN1; SMN2KMT2A | |
| SCHEMBL2852714 | 0.83 | TAAR1 (0.48) | TAAR1ALDH1A1TRPV1SMN1; SMN2KMT2A | |
| SCHEMBL2852542 | 0.80 | GCGR (0.45) | TAAR1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |