SCHEMBL2858286

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2858300	0.93	MAPT (0.47)	KDM4EALDH1A1HPGDKMT2ANPC1
	SCHEMBL2861144	0.90	KDM4E (0.42)	KDM4EALDH1A1GAANPC1MAPT
	SCHEMBL2856371	0.90	KDM4E (0.45)	KDM4EFLT3PKMAKR1C3ALDH1A1
	SCHEMBL2871399	0.90	KDM4E (0.39)	KDM4EFLT3ALDH1A1HPGDKMT2A
	SCHEMBL2866517	0.89	KDM4E (0.41)	KDM4EALDH1A1GAANPC1MAPT
	SCHEMBL2859038	0.89	KDM4E (0.40)	KDM4EALDH1A1GAAHPGDMEN1
	SCHEMBL2856163	0.89	KDM4E (0.38)	KDM4EFLT3PKMMEN1KMT2A
	SCHEMBL2856148	0.89	SMN1; SMN2 (0.39)	KDM4EAKR1C3MEN1KMT2ANPC1
	SCHEMBL2857228	0.89	KDM4E (0.39)	KDM4EFLT3ALDH1A1GAAHPGD
	SCHEMBL2859968	0.88	KDM4E (0.54)	KDM4EALDH1A1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.