Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 7/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16033289 | 0.77 | AHR (0.39) | PIK3CGAHRGAAAPPNPC1 | |
| SCHEMBL29036635 | 0.73 | PIK3CG (0.47) | PIK3CGAHRGAAAPPNPC1 | |
| SCHEMBL21373266 | 0.71 | MAPK1 (0.36) | GAANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL22612479 | 0.71 | KDM4E (0.34) | RAB9ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL28548228 | 0.68 | AHR (0.38) | PIK3CGAHRGAANPC1RAB9A | |
| SCHEMBL21373269 | 0.64 | — | — | |
| SCHEMBL1500151 | 0.64 | PIK3CG (0.55) | PIK3CGAPPNPC1RAB9ATSHR | |
| SCHEMBL16051979 | 0.62 | GAA (0.49) | GAANPC1RAB9ATSHRMAPK10 | |
| SCHEMBL16082934 | 0.61 | GAA (0.44) | PIK3CGGAAAPPNPC1RAB9A | |
| SCHEMBL17224416 | 0.61 | PIK3CG (0.37) | PIK3CGAHRGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484600-B | URAT1 inhibitors for promoting uric acid excretion | 江苏新元素医药科技有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-108084186-B | URAT1 inhibitor and application thereof | 江苏新元素医药科技有限公司 | 2021-06-25 | — | — | CN | disclosed |