Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.66 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.66 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.66 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.66 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.66 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | PRNP | P04156 | 1/20 | 0.66 |
| ▸ | APP | P05067 | 1/20 | 0.66 |
| ▸ | NQO2 | P16083 | 1/20 | 0.66 |
| ▸ | MTOR | P42345 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896415 | 0.87 | NR4A2 (0.72) | NR4A2CHRM2CHRM4CHRM5ADRA2A | |
| Bidesethyl Chloroquine SCHEMBL17706108 | 0.86 | CHRM2 (0.71) | NR4A2CHRM2CHRM4CHRM5ADRA2A | |
| Bidesethyl Chloroquine SCHEMBL29625380 | 0.86 | CHRM2 (0.71) | NR4A2CHRM2CHRM4CHRM5ADRA2A | |
| Bidesethyl Chloroquine SCHEMBL6659403 | 0.86 | CHRM2 (0.71) | NR4A2CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL24686036 | 0.86 | CHRM2 (0.74) | NR4A2CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL16702725 | 0.86 | NR4A2 (0.67) | NR4A2CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL7835332 | 0.85 | NR4A2 (0.70) | NR4A2CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL12967486 | 0.85 | CHRM2 (0.77) | NR4A2CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL17704778 | 0.85 | CHRM2 (0.77) | NR4A2CHRM2CHRM4CHRM5ADRA2A | |
| Hydrochloric Acid SCHEMBL7835555 | 0.84 | NR4A2 (0.68) | NR4A2CHRM2CHRM4CHRM5ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109640993-B | Pharmaceutical composition for preventing or treating diabetes comprising amodiaquine and antidiabetic agent as active ingredients | 诺麦塔制药有限公司 | 2021-07-09 | — | — | CN | disclosed |