Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 6/20 | 0.58 |
| ▸ | GSK3A | P49840 | 3/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.58 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.58 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28591425 | 0.83 | KMT2A (0.60) | KDM4ELMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL29404948 | 0.83 | KMT2A (0.54) | RIOK2GSK3AMAPK10KDM4EGAA | |
| SCHEMBL28917003 | 0.83 | KMT2A (0.54) | RIOK2GSK3AMAPK10KDM4EGAA | |
| SCHEMBL28917422 | 0.81 | KMT2A (0.55) | RIOK2KDM4EGAAKMT2AMEN1 | |
| SCHEMBL28591047 | 0.81 | KMT2A (0.55) | KDM4EGAAKMT2AMEN1SLC6A2 | |
| SCHEMBL28585150 | 0.80 | HTT (0.61) | RIOK2MAPK10KDM4ELMNAGAA | |
| SCHEMBL28604916 | 0.77 | KMT2A (0.51) | RIOK2GAAKMT2AMEN1NLRP3 | |
| SCHEMBL24195991 | 0.74 | MEN1 (0.62) | RIOK2GSK3AMAPK10MAPK8HIPK1 | |
| SCHEMBL5453254 | 0.73 | GAA (0.58) | GAASMN1; SMN2KMT2AMEN1SLC6A2 | |
| SCHEMBL1520280 | 0.73 | MEN1 (0.65) | RIOK2KMT2AMEN1NLRP3NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135911-B | Method for preparing pyridotriazolone compounds by flow chemistry | 浙江工业大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-113121526-B | Method for preparing pyridotriazolone compounds by oxidation rearrangement | 浙江工业大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-113136594-B | Method for electrochemically synthesizing pyridotriazolone compounds | 浙江工业大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-113136594-A | Method for electrochemically synthesizing pyridotriazolone compounds | 浙江工业大学 | 2021-07-20 | — | — | CN | disclosed |
| CN-113135911-A | Method for preparing pyridotriazolone compounds by flow chemistry | 浙江工业大学 | 2021-07-20 | — | — | CN | disclosed |
| CN-113121526-A | Method for preparing pyridotriazolone compounds by oxidation rearrangement | 浙江工业大学 | 2021-07-16 | — | — | CN | disclosed |