Fluoride

Fluoride

SCHEMBL28587768

Cc1cc(C)c(C)c(C)c1C.F.F

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.37
TSHR P16473 2/20 0.37
MAPK1 P28482 1/20 0.37
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31
ALDH1A1 P00352 2/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
ACHE P22303 1/20 0.30
TP53 P04637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL120101 0.96 TSHR (0.39) CYP3A4TSHRMAPK1PGK1PGK2
Ammonia Solution, Strong SCHEMBL27547044 0.92 CYP3A4 (0.37) CYP3A4TSHRMAPK1PGK1PGK2
SCHEMBL10411849 0.92 CYP3A4 (0.37) CYP3A4TSHRMAPK1PGK1PGK2
SCHEMBL10346431 0.92 CYP3A4 (0.37) CYP3A4TSHRMAPK1PGK1PGK2
Hexamethylbenzene SCHEMBL10345657 0.92 CYP3A4 (0.37) CYP3A4TSHRMAPK1PGK1PGK2
SCHEMBL5182505 0.92 CYP3A4 (0.37) CYP3A4TSHRMAPK1PGK1PGK2
Methane SCHEMBL27481300 0.92 CYP3A4 (0.37) CYP3A4TSHRMAPK1PGK1PGK2
SCHEMBL2724509 0.92 CYP3A4 (0.44) CYP3A4TSHRMAPK1PGK1PGK2
Bromide SCHEMBL28157338 0.92 CYP3A4 (0.37) CYP3A4TSHRMAPK1PGK1PGK2
Ethylene SCHEMBL27763844 0.88 CYP3A4 (0.35) CYP3A4TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108358767-B Pentabenzyl benzene-containing difluoride monomer, preparation method and application thereof in polyaryletherketone functional film 吉林大学 2021-06-04 CN claimed
CN-108358767-B Pentabenzyl benzene-containing difluoride monomer, preparation method and application thereof in polyaryletherketone functional film 吉林大学 2021-06-04 CN disclosed