SCHEMBL2858788

SCHEMBL2858788

CC1CCCC(CC(C(=O)O)C(=O)O)C1CC(C(=O)O)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 7/20 0.33
PTGS2 P35354 6/20 0.33
MT-CO1 P00395 1/20 0.33
MT-CO2 P00403 1/20 0.33
GRIN2D O15399 5/20 0.31
GRIN3B O60391 5/20 0.31
GRIN1 Q05586 5/20 0.31
GRIN2A Q12879 5/20 0.31
GRIN2B Q13224 5/20 0.31
GRIN2C Q14957 5/20 0.31
GRIN3A Q8TCU5 5/20 0.31
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2855911 0.96 EPHX1 (0.34) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2861061 0.95 GRIN2D (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2862790 0.95 GRIN2D (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2852642 0.89 JAK2 (0.33) PTGS1PTGS2MT-CO1MT-CO2
SCHEMBL2855943 0.89
SCHEMBL2856522 0.88 EPHX1 (0.34) EPHX1
SCHEMBL2852629 0.82 HMGCR (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2857816 0.80
SCHEMBL2857737 0.80 GRIN2D (0.42) PTGS1PTGS2MT-CO1MT-CO2GRIN2D
SCHEMBL2853679 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104640887-A Production method for solid catalyst component for polymerizing olefins, catalyst for polymerizing olefins, and production method for polymerized olefins TOHO TITANIUM CO LTD 2015-05-20 CN disclosed
CN-104640886-A PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, CATALYST FOR POLYMERIZING OLEFINS, AND PRODUCTION METHOD FOR POLYMERIZED OLEFINS TOHO TITANIUM CO LTD 2015-05-20 CN disclosed
CN-104470953-A Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer TOHO TITANIUM CO LTD 2015-03-25 CN disclosed
US-8822366-B2 Solid titanium catalyst component, catalyst for olefin polymerization and process for polymerizing olefin MITSUI CHEMICALS, INC. (JP) 2014-09-02 US disclosed
CN-102159608-B Propylene-based block copolymer and composition containing the copolymer, and molded body obtained therefrom MITSUI CHEMICALS INC 2014-05-21 CN disclosed
CN-102159596-B Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO LTD 2014-05-07 CN disclosed
EP-2206731-B1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD MITSUI CHEMICALS INC (JP) 2013-08-28 EP disclosed
US-20100227991-A1 SOLID TITANIUM CATALYST COMPONENT, CATALIST FOR OLEFIN POLYMERIZATION AND PROCESS FOR POLYMERIZING OLEFIN MITSUI CHEMICALS, INC. (JP) 2010-09-09 US disclosed
EP-2206731-A1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD Mitsui Chemicals, Inc. (JP) 2010-07-14 EP disclosed