Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | USP14 | P54578 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28588310 | 1.00 | MAPK8 (0.35) | MAPK8EPHX1PARP1USP14DPP4 | |
| SCHEMBL30180399 | 1.00 | MAPK8 (0.35) | MAPK8EPHX1PARP1USP14DPP4 | |
| SCHEMBL31689666 | 0.95 | MAPK8 (0.36) | MAPK8EPHX1PARP1USP14DPP4 | |
| SCHEMBL28585707 | 0.92 | EPHX1 (0.36) | MAPK8EPHX1PARP1USP14DPP4 | |
| SCHEMBL28585708 | 0.92 | EPHX1 (0.36) | MAPK8EPHX1PARP1USP14DPP4 | |
| SCHEMBL30180486 | 0.92 | EPHX1 (0.36) | MAPK8EPHX1PARP1USP14DPP4 | |
| SCHEMBL30180583 | 0.92 | F10 (0.41) | MAPK8EPHX1PARP1USP14DPP4 | |
| SCHEMBL28916256 | 0.92 | F10 (0.41) | MAPK8EPHX1PARP1USP14DPP4 | |
| SCHEMBL28916257 | 0.92 | F10 (0.41) | MAPK8EPHX1PARP1USP14DPP4 | |
| SCHEMBL28580848 | 0.90 | MAPK8 (0.35) | MAPK8EPHX1PARP1USP14DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |